Barrie Chase began her film career as a dancer in the chorus, appearing in such movies as Hans Christian Andersen (1952), Call Me Madam (1953), Brigadoon (1954), White Christmas (1954), Daddy Long Legs (1955), KISMET (1955), Silk Stockings (1957), Les Girls (1957), and Pal Joey (1957). In The Opposite Sex (1956), she was featured in Dick Shawn’s psychiatrist number with Joan Collins and Carolyn Jones. In 1958, Chase had a featured role in Mardi Gras, which she followed by starring in movies such as The George Raft Story (1961), CAPE FEAR (1962), IT’S A MAD MAD MAD MAD WORLD (1963) and The Flight of the Phoenix (1965).
On television, Barrie Chase danced on The Hollywood Palace many times and appeared in other variety shows like Perry Como’s Kraft Music Hall, The Dean Martin Comedy Hour and The Carol Burnett Show. She appeared on dramatic television shows including Have Gun – Will Travel, Burke’s Law and Bonanza, in an episode written by her brother, Frank Chase. Chase starred in the television special The Seasons of Youth (1961), in which she danced with the legendary Bob Fosse. In 1958, Fred Astaire asked her to be his dancing partner on his first television special, An Evening with Fred Astaire. The successful, Emmy-winning An Evening with Fred Astaire spawned three further specials, and Chase returned to dance with Astaire in each one. In 1964, Chase starred again with Fred Astaire in Think Pretty, a musical special on Bob Hope Presents the Chrysler Theatre. She appeared on What’s My Line? and talk shows including Edward R. Murrow’s Person to Person, The Tonight Show Starring Johnny Carson, The Merv Griffin Show and The Mike Douglas Show. She also appeared on television programs in Germany, England, Sweden, and on RAI Studio Uno in Italy.